Maryland Route 355 (MD 355) is a 36.75-mile (59.14 km) north–south road in western central Maryland in the United States. The southern terminus of the route is in Bethesda in Montgomery County, where Wisconsin Avenue meets the county's border with Washington, D.C. The northern terminus is just north of a bridge over Interstate 70 (I-70)/U.S. Route 40 (US 40) in the city of Frederick in Frederick County, where the road continues north as Market Street through Frederick towards MD 26.