Maryland Route 818 is a state highway in the U.S. state of Maryland. Known as Main Street, the state highway runs 2.62 miles (4.22 km) between two intersections with U.S. Route 113 on the north and south sides of Berlin in Worcester County. MD 818 is the original 1927 alignment of US 113 through Berlin. The state highway was designated shortly after US 113's bypass of Berlin was completed in the late 1950s.

U.S. Route 113 (US 113) is a U.S. Highway that is a spur of US 13 in the U.S. states of Maryland and Delaware. The route runs 74.75 miles (120.30 km) from US 13 in Pocomoke City, Maryland, north to Delaware Route 1 (DE 1) in Milford, Delaware. In conjunction with DE 1, US 113 is one of two major north–south highways on the Delmarva Peninsula that connect Dover with Pocomoke City and the Eastern Shore of Virginia. The U.S. Highway is the primary north–south highway in Worcester County, Maryland, where it connects Pocomoke City with Snow Hill and Berlin. US 113 is one of three major north–south highways in Sussex County, Delaware, where it connects Selbyville, Millsboro, and Georgetown with Milford. While US 113 does not pass through Ocean City or the Delaware Beaches, the U.S. Highway intersects several highways that serve the Atlantic seaboard resorts, including US 50, Maryland Route 90 (MD 90), US 9, DE 404, DE 16, and DE 1. US 113 is a four-lane divided highway for its whole length.