The Mashantucket Pequot Tribal Nation is a federally recognized American Indian tribe in the state of Connecticut. They are descended from the Pequot people, an Algonquian-language tribe that dominated the southern New England coastal areas, and they own and operate Foxwoods Resort Casino within their reservation in Ledyard, Connecticut. As of 2018, Foxwoods Resort Casino is one of the largest casinos in the world in terms of square footage, casino floor size, and number of slot machines, and it was one of the most economically successful in the United States until 2007, but it became deeply in debt by 2012 due to its expansion and changing conditions.

The Pequot are a Native American people of Connecticut. The modern Pequot are members of the federally recognized Mashantucket Pequot Tribe, four other state-recognized groups in Connecticut including the Eastern Pequot Tribal Nation, or the Brothertown Indians of Wisconsin. They historically spoke Pequot, a dialect of the Mohegan-Pequot language, which became extinct by the early 20th century. Some tribal members are undertaking revival efforts.