Maspeth is a residential and commercial community in the borough of Queens in New York City. It was founded in the early 17th century by Dutch and English settlers. Neighborhoods sharing borders with Maspeth are Woodside to the north; Sunnyside to the northwest; Greenpoint, Brooklyn to the west; East Williamsburg, Brooklyn to the southwest; Fresh Pond and Ridgewood to the south; and Middle Village and Elmhurst to the east.

Newtown Creek, a 3.5-mile (6-kilometer) long tributary of the East River, is an estuary that forms part of the border between the boroughs of Brooklyn and Queens, in New York City. Channelization made it one of the most heavily-used bodies of water in the Port of New York and New Jersey and thus one of the most polluted industrial sites in the United States, containing years of discarded toxins, an estimated 30,000,000 US gallons of spilled oil, including the Greenpoint oil spill, raw sewage from New York City's sewer system, and other accumulation from a total of 1,491 sites.