The Mass Effect: Andromeda book series consists of a trilogy of science fiction novels based on the Mass Effect series of video games. The books in the series are Nexus Uprising (2017), Initiation (2017), and Annihilation (2018). All three books are released in paperback, e-book, and audiobook. The audiobook formats of Nexus Uprising and Initiation are narrated by Fryda Wolff, the voice of Sara Ryder, while the Annihilation audiobook is narrated by Tom Taylorson, the voice of Scott Ryder.

Mass Effect is a military science fiction media franchise created by Casey Hudson. The franchise depicts a distant future where humanity and several alien civilizations have colonized the galaxy using technology left behind by advanced precursor civilizations.