Route 116 is a 68.26-mile-long (109.85 km) north–south state highway in Massachusetts. The route runs from Route 20A in Springfield through mill towns, college towns and rural towns, crossing the Connecticut River three times before finally ending at Route 8 in Adams.

Adams is a town in northern Berkshire County, Massachusetts, United States. It is part of the Pittsfield, Massachusetts Metropolitan Statistical Area. The population was 8,166 at the 2020 census.