Route 60 is a 14.33-mile-long (23.06 km) east–west state highway running through the northern suburbs of Boston. Its western terminus is at U.S. Route 20 in Waltham and its eastern terminus is at Route 1A and Route 16 in Revere.

U.S. Route 20 (US 20) runs its easternmost 153 miles (246 km) in the U.S. state of Massachusetts. The highway crosses the state border from New Lebanon, New York, into Hancock and runs eastward to Boston, where it ends at Route 2 in Kenmore Square. It spends the vast majority of its journey paralleling I-90, which has largely superseded US 20 for through travel. Still, US 20 directly serves many towns and local business areas which the turnpike bypasses.