Matewan is a town in Mingo County, West Virginia, United States at the confluence of the Tug Fork River and Mate Creek. The population was 412 at the 2020 census, down from 499 in 2010. The Norfolk Southern Railway's Pocahontas District passes through the town. It was a key site of the Coal Wars and the location of the Battle of Matewan in 1920.

Mingo County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 23,568. Its county seat and largest city is Williamson. Created in 1895, Mingo is West Virginia's newest county, named for the historic Iroquoian Mingo people.