Matooskie, also known as Anne "Nancy" McKenzie, was a First Nations woman of the Chipewyan nation in Canada. The daughter of Scottish-Canadian fur trader Roderick Mackenzie, Matooskie was abandoned by her father as a young girl, and was left in the care of North West Company trader John Stuart. She was later abandoned by her first husband, John George McTavish. Supported by the Hudson's Bay Company, Matooskie and her family moved to various Hudson's Bay outposts across Western Canada, before settling at Fort Vancouver in the Columbia District following the death of her second husband. In the later years before her death in 1851, she accompanied her daughter and son-in-law.

The Chipewyan are a Dene Indigenous Canadian people of the Athabaskan language family, whose ancestors are identified with the Taltheilei Shale archaeological tradition. They are part of the Northern Athabascan group of peoples, and hail from what is now Western Canada.