May Pen is the capital and largest town in the parish of Clarendon in Middlesex County, Jamaica. It is located on the Rio Minho river, and is a major market centre for the parish. The population was 61,548 at the 2011 census increasing from 59,550 in 2001, including the surrounding suburbs of Sandy Bay, Mineral Heights, Hazard, Palmers Cross, Denbigh, Race Track, and Four Paths among others. The town has a mayor.

Clarendon is a parish in Jamaica. It is located on the south of the island, roughly halfway between the island's eastern and western ends. Located in the county of Middlesex, it is bordered by Manchester on the west, Saint Catherine in the east, and in the north by Saint Ann. Its capital and largest town is May Pen.