Mayday at 40,000 Feet! is a 1976 American made-for-television drama film, directed by Robert Butler. The film stars David Janssen, Don Meredith and Christopher George, along with an all-star cast primarily playing the roles of passengers and crew aboard an airliner in crisis.

David Janssen was an American film and television actor who is best known for his starring role as Richard Kimble in the television series The Fugitive (1963–1967). Janssen also had the title roles in three other series: Richard Diamond, Private Detective; O'Hara, U.S. Treasury; and Harry O.