Mayfield Heights is a city in Cuyahoga County, Ohio, United States. The population was 20,351 at the 2020 census. An eastern suburb of Cleveland, it is part of the Cleveland metropolitan area.

Cuyahoga County is a large urban county located in the northeastern part of the U.S. state of Ohio. The county seat and largest city is Cleveland. As of the 2020 census, its population was 1,264,817, making it the second-most populous county in the state.