The mayor of Rome is an elected politician who, along with the Rome City Council of 48 members, is accountable for the strategic government of Rome. As Rome is a comune speciale since 2009, the office is different from the offices of the other Italian cities. The title is the equivalent of Lord Mayor in the meaning of an actual executive leader.

Roberto Gualtieri is an Italian historian, academic and politician of the Democratic Party (PD), incumbent Mayor of Rome since 2021 and Minister of Economy and Finances in the second government of Giuseppe Conte from 2019 until 2021. He previously was a Member of the European Parliament from 2009 to 2019, where he chaired the influential Economic and Monetary Affairs Committee within the Parliament from 2014 until 2019.