The mayor of Valenzuela, a highly urbanized city in northern Metro Manila, Philippines, is the official head and chief executive of Valenzuela. He leads on enforcing city ordinances and improving public services. The mayor has a term of office of three years, but has a maximum electoral tenure of three consecutive terms. Inaugural holder of the office was Pío Valenzuela (1869–1956), served from 1899 to 1901, whom the city received its name.

Pío Valenzuela y Alejandrino was a Filipino physician and revolutionary leader. At the age of 23, he joined the society of Katipunan, a movement which sought the independence of the Philippines from Spanish colonial rule and started the Philippine Revolution. Together with Andrés Bonifacio and Emilio Jacinto, they formed the secret chamber of the society called Camara Reina. He took charge of the publication of Ang Kalayaan, Katipunan's first and only official publication. He was the one who tried to convince the exiled José Rizal to join the revolutionary movement.