McCormick Place is the largest convention center in North America. It consists of four interconnected buildings and one indoor arena sited on and near the shore of Lake Michigan, about 2 mi (3.2 km) south of downtown Chicago, Illinois, United States. McCormick Place hosts numerous trade shows and meetings. The largest regular events are the Chicago Auto Show each February, the International Home and Housewares Show each March, the National Restaurant Association Annual Show each May, and the International Manufacturing Technology Show in the fall every other year.

The ongoing COVID-19 pandemic began in the U.S. state of Illinois on January 24, 2020, when a woman in Chicago, who had just returned from the pandemic's place of origin in Wuhan, Hubei, China, tested positive for the virus. This was the second case of COVID-19 in the United States during the pandemic. The woman's husband was diagnosed with the disease a few days later, the first known case of human-to-human transmission in the United States. Community transmission was not suspected until March 8, when a case with no connection to other cases or recent travel was confirmed.