The Donald and Sylvia McLaughlin Natural Reserve is a 7,050-acre (28.5 km2) University of California Natural Reserve System reserve in the Blue Ridge Berryessa Natural Area, in Napa and Lake counties of California. The site is owned by the Homestake Mining Company, and is the site of the now-closed McLaughlin Mine.

The Sulphur Bank Mine is located near Clearlake Oaks and Clear Lake in Lake County, California. The 150-acre (0.61 km2) mine became one of the most noted mercury producers in the world.