McVicker's Theater (1857–1984) was a playhouse in Chicago, Illinois, United States. Built for actor James Hubert McVicker, the theater was the leading stage for comedic plays in Chicago's early years. It often hosted performances by Edwin Booth, who married McVicker's daughter and was once targeted there in an attempted murder. Adler & Sullivan designed a remodel in 1883. Although destroyed in two fires, including the Great Chicago Fire, McVicker's remained an operating theater until 1984. It was demolished the next year.

Edwin Thomas Booth was an American actor who toured throughout the United States and the major capitals of Europe, performing Shakespearean plays. In 1869, he founded Booth's Theatre in New York. Some theatrical historians consider him the greatest American actor, and the greatest Prince Hamlet, of the 19th century. His achievements are often overshadowed by his relationship with his younger brother, actor John Wilkes Booth, who assassinated the 16th president of the United States, Abraham Lincoln.