Me and Earl and the Dying Girl is a 2015 American coming-of-age comedy-drama film directed by Alfonso Gomez-Rejon from a screenplay by Jesse Andrews, based on Andrews' 2012 novel of the same name. The film stars Thomas Mann, RJ Cyler and Olivia Cooke. It follows a socially awkward teenage boy who, along with an acquaintance, befriends a classmate after she is diagnosed with cancer. The film premiered at the 2015 Sundance Film Festival and was released in the United States on June 12, 2015, by Fox Searchlight Pictures. It received positive reviews from critics, who praised the screenplay and cast.

Alfonso Gomez-Rejon is an American film and television director. He made his directorial film debut with the slasher film The Town That Dreaded Sundown (2014). He has since directed the coming of age film Me and Earl and the Dying Girl (2015), and the historical drama The Current War (2017).