Medardo Mairena Sequeira is a Nicaraguan farmer and coordinator of the peasant (campesino) movement. Mairena has worked in the peasant anti-canal movement since 2013 and has been an active opposition leader since the national protests broke out in late April 2018, participating in the National Dialogue between protestors and the government of Daniel Ortega, mediated by the Catholic Church. Two months later he became one of a large number of dissidents arrested and prosecuted for terrorism; Mairena was sentenced to 261 years in prison, serving one year before he was released under a negotiated Amnesty Law.

General elections were held in Nicaragua on 7 November 2021 to elect the President, the National Assembly and members of the Central American Parliament.