Median lethal dose
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In toxicology, the median lethal dose, LD50, LC50 or LCt50 is a toxic unit that measures the lethal dose of a given substance. The value of LD50 for a substance is the dose required to kill half the m
Negative values of the decimal logarithm of the median lethal dose LD50 (−log10(LD50)) on a linearized toxicity scale encompassing 11 orders of magnitude. Water occupies the lowest toxicity position (1) while the toxicity scale is dominated by the botulinum toxin (12).
Botulinum toxin
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Botulinum toxin, botulinum neurotoxin, or botox is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species, and it is considered the deadliest known natural substance
Median lethal dose
…on animals such as laboratory mice. In 2011, the U.S. Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug botox without animal tests. The LD50 is usually expressed as the mass of substance administered per unit mass of test subject, typically as milligrams of…
Botulinum toxin being injected in the human face
Doctor performing botulinum toxin injection