Melanopsin
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Melanopsin is a type of photopigment belonging to a larger family of light-sensitive retinal proteins called opsins and encoded in humans by the gene OPN4. In the mammalian retina, there are two addit
Nerve cells containing melanopsin are shown in blue in the spread out retina.
Intrinsically photosensitive retinal ganglion cells, also called photosensitive retinal ganglion cells, or melanopsin-containing retinal ganglion cells, are a type of neuron in the retina of the mamma
Melanopsin
…visual images: rhodopsin and photopsin (types I, II, and III) in the rod and cone photoreceptor cells, respectively. In humans, melanopsin is found in intrinsically photosensitive retinal ganglion cells (ipRGCs). It is also found in the iris of mice and primates. Melanopsin is also found in rats, amphioxus, and other chordates. ipRGCs are photoreceptor…
An ipRGC, shown here as a complied image of the retina from proximal inner nuclear layer to the ganglion cell layer with fluorescent labeling of melanopsin
Synaptic inputs and outputs of ipRGCs and their corresponding location in the brain