Melbourne tram route 75 is operated by Yarra Trams on the Melbourne tram network from Vermont South to Central Pier. The 22.8 kilometre route is operated out of Camberwell depot with A and B class trams. It is the longest route on the network.

Yarra Trams is the trading name of the operator of the tram network in Melbourne, Australia, which is owned by VicTrack and leased to Yarra Trams by the Victorian Department of Transport and Planning. The current franchise is operated by Keolis Downer. As at May 2014, Yarra Trams operate 487 trams, across 26 tram routes and a free City Circle tourist tram, over 1,763 tram stops. With 250 km (155.3 mi) of double track, Melbourne's tram network is the largest in the world.