Memnon of Rhodes was a prominent Rhodian Greek commander in the service of the Achaemenid Empire. Related to the Persian aristocracy by the marriage of his sister to the satrap Artabazus II, together with his brother Mentor he served the Persian king for most of his life, and played an important role during the invasion of Alexander the Great and the decades before that.

The siege of Halicarnassus was fought between Alexander the Great and the Achaemenid Persian Empire in 334 BC. Alexander, who had no navy, was constantly being threatened by the Persian navy. It continuously attempted to provoke an engagement with Alexander, who would not oblige them. Eventually, the Persian fleet sailed to Halicarnassus, in order to establish a new defense. Ada of Caria, the former queen of Halicarnassus, had been driven from her throne by her younger brother Pixodarus of Caria. When Pixodarus died, Persian King Darius had appointed Orontobates satrap of Caria, which included Halicarnassus in its jurisdiction. On the arrival of Alexander in 334 BC, Ada, who was in possession of the fortress of Alinda, surrendered the fortress to him.