Mendon is a village in St. Joseph County in the U.S. state of Michigan. The population was 870 at the 2010 census. The village is located within Mendon Township.

St. Joseph County is a county located in the U.S. state of Michigan, on the central southern border with Indiana. As of the 2020 United States Census, the population was 60,939. The county seat is Centreville.