Menifee County is a county located in the U.S. state of Kentucky. As of the 2020 census, the population was 6,113, making it the fifth-least populous county in Kentucky. Its county seat is Frenchburg. The county is named for Richard Hickman Menefee, U.S. Congressman, although the spelling has changed. It is a prohibition or dry county. Menifee County is part of the Mount Sterling, KY Micropolitan Statistical Area, which is also included in the Lexington-Fayette–Richmond–Frankfort, KY combined statistical area. It is located in the foothills of the Cumberland Plateau.

Frenchburg is a home rule-class city in Menifee County, Kentucky, in the United States. The population was 601 at the 2020 census, up from 486 in 2010. It is the seat and only incorporated city in its rural county. It is located at the junction of U.S. Route 460 and Kentucky Route 36. Logging is the primary industry.