The Menil Collection, located in Houston, Texas, refers either to a museum that houses the art collection of founders John de Menil and Dominique de Menil, or to the collection itself of paintings, sculptures, prints, drawings, photographs and rare books.

John de Ménil was a Franco-American businessman, philanthropist, and art patron. He was the founding president of the International Foundation for Art Research (IFAR) in New York. With his wife, Dominique de Menil, he established the Menil Collection, a free museum designed by Renzo Piano and built in 1986 to preserve and exhibit their world-class contemporary art collection.