Merrylands railway station is located on the Main South line, serving the Sydney suburb of Merrylands. It is served by Sydney Trains T2 Inner West & Leppington and T5 Cumberland line services.

The Main Southern Railway is a major railway in New South Wales, Australia. It runs from Sydney to Albury, near the Victorian border. The line passes through the Southern Highlands, Southern Tablelands, South West Slopes and Riverina regions.