A mesa is an isolated, flat-topped elevation, ridge or hill, which is bounded from all sides by steep escarpments and stands distinctly above a surrounding plain. Mesas characteristically consist of flat-lying soft sedimentary rocks capped by a more resistant layer or layers of harder rock, e.g. shales overlain by sandstones. The resistant layer acts as a caprock that forms the flat summit of a mesa. The caprock can consist of either sedimentary rocks such as sandstone and limestone; dissected lava flows; or a deeply eroded duricrust. Unlike plateau, whose usage does not imply horizontal layers of bedrock, e.g. Tibetan Plateau, the term mesa applies exclusively to the landforms built of flat-lying strata. Instead, flat-topped plateaus are specifically known as tablelands.

The Colorado Plateau, also known as the Colorado Plateau Province, is a physiographic and desert region of the Intermontane Plateaus, roughly centered on the Four Corners region of the southwestern United States. This province covers an area of 336,700 km2 (130,000 mi2) within western Colorado, northwestern New Mexico, southern and eastern Utah, northern Arizona, and a tiny fraction in the extreme southeast of Nevada. About 90% of the area is drained by the Colorado River and its main tributaries: the Green, San Juan, and Little Colorado. Most of the remainder of the plateau is drained by the Rio Grande and its tributaries.