Mesih Pasha or Misac Pasha was an Ottoman statesman of Byzantine Greek origin, being a nephew of the last Roman emperor, Constantine XI Palaiologos. He served as Kapudan Pasha of the Ottoman Navy and was Grand Vizier of the Ottoman Empire in 1501.

The fall of Constantinople, also known as the conquest of Constantinople, was the capture of the capital of the Byzantine Empire by the Ottoman Empire. The city was captured on 29 May 1453 as part of the culmination of a 53-day siege which had begun on 6 April.