Mesoamerican pyramids form a prominent part of ancient Mesoamerican architecture. Although similar in some ways to Egyptian pyramids, these New World structures have flat tops and stairs ascending their faces, more similar to ancient Mesopotamian Ziggurats. The largest pyramid in the world by volume is the Great Pyramid of Cholula, in the east-central Mexican state of Puebla. The builders of certain classic Mesoamerican pyramids have decorated them copiously with stories about the Hero Twins, the feathered serpent Quetzalcoatl, Mesoamerican creation myths, ritualistic sacrifice, etc. written in the form of Maya script on the rises of the steps of the pyramids, on the walls, and on the sculptures contained within.

Mesoamerican architecture is the set of architectural traditions produced by pre-Columbian cultures and civilizations of Mesoamerica, traditions which are best known in the form of public, ceremonial and urban monumental buildings and structures. The distinctive features of Mesoamerican architecture encompass a number of different regional and historical styles, which however are significantly interrelated. These styles developed throughout the different phases of Mesoamerican history as a result of the intensive cultural exchange between the different cultures of the Mesoamerican culture area through thousands of years. Mesoamerican architecture is mostly noted for its pyramids, which are the largest such structures outside of Ancient Egypt.