Metropolitan State University of Denver is a public university in Denver, Colorado. It is located on the Auraria Campus, along with the University of Colorado Denver and the Community College of Denver, in downtown Denver, adjacent to Speer Boulevard and Colfax Avenue. MSU Denver had an enrollment of 16,345 undergraduate students in the fall of 2023.

The University of Colorado Denver is a public research university located in downtown Denver, Colorado. It is part of the University of Colorado system. Established in 1912 as an extension of the University of Colorado Boulder, CU Denver attained university status and became an independent institution in 1973. CU Denver is the largest research university in Colorado, and is classified among R1: Doctoral Universities - Very High Research Activity. The university's graduate programs award more master's degrees than any other institution in the state, serving roughly 5,000 students annually.