Meurthe-et-Moselle is a département in the Grand Est region of France, named after the rivers Meurthe and Moselle. Its prefecture and largest city is Nancy and it borders the departments of Meuse to the west, Vosges to the south, Moselle and Bas-Rhin and it borders the Belgian province of Luxembourg and the country of Luxembourg by the canton of Esch-sur-Alzette to the north. It had a population of 733,760 in 2019.

In the administrative divisions of France, the department is one of the three levels of government under the national level, between the administrative regions and the communes. Ninety-six departments are in metropolitan France, with an additional five constituting overseas departments, which are also classified as overseas regions. Departments are further subdivided into 333 arrondissements and 2,054 cantons. These last two levels of government have no political autonomy, instead serving as the administrative basis for the local organisation of police, fire departments as well as, in certain cases, elections.