Meyersdale is a borough in Somerset County, Pennsylvania, United States, situated on the Casselman River, 73 miles (117 km) southeast of Pittsburgh. It is part of the Johnstown, Pennsylvania, Metropolitan Statistical Area.

Somerset County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 74,129. Its county seat is Somerset. The county was created from part of Bedford County on April 17, 1795, and named after the county of Somerset in England. The county is part of the Southwest Pennsylvania region of the state.