Mfantsipim is an all-boys boarding secondary school in Cape Coast, Ghana, established by the Methodist Church in 1876 to foster intellectual, moral, and spiritual growth on the then Gold Coast. Its founding name was Wesleyan High School and the first headmaster was James Picot, a French scholar, who was only 18 years old on his appointment.

Cape Coast is a city, fishing port, and the capital of Cape Coast Metropolitan District and Central Region of Ghana. It is one of the country's most historic cities, a World Heritage Site, home to the Cape Coast Castle, with the Gulf of Guinea situated to its south. According to the 2021 census, Cape Coast had a settlement population of 189,925 people. The language of the people of Cape Coast is Fante.