Michael Reese Hospital and Medical Center was an American hospital located in the Bronzeville neighborhood of Chicago, Illinois. Founded in 1881, Michael Reese Hospital was a major research and teaching hospital and one of the oldest and largest hospitals in Chicago, Illinois. It was located at 2929 S. Ellis Avenue on the near south side of Chicago, next to Lake Shore Drive which lies along Lake Michigan. The hospital closed its Internal Medicine Residency at the end of the 2007–2008 academic year and finished transferring patients to Mercy Hospital and Medical Center before the end of 2008. The 48-acre campus was then vacated by January 2009. From 2007 to its closing, Michael Reese had been owned by Envision Hospital Corporation of Scottsdale, Arizona. The hospital officially closed August 31, 2009. At one time, the hospital had a large health plan which included 300,000 patients; at the time of the hospital's closure the health plan was terminated and it only had 2,900 clients. The streets through the campus were closed and demolition began in October 2009.

Douglas, on the South Side of Chicago, Illinois, is one of Chicago's 77 community areas. The neighborhood is named for Stephen A. Douglas, Illinois politician and Abraham Lincoln's political foe, whose estate included a tract of land given to the federal government. This tract later was developed for use as the Civil War Union training and prison camp, Camp Douglas, located in what is now the eastern portion of the Douglas neighborhood. Douglas gave that part of his estate at Cottage Grove and 35th to the Old University of Chicago. The Chicago 2016 Olympic bid planned for the Olympic Village to be constructed on a 37-acre (15 ha) truck parking lot, south of McCormick Place, that is mostly in the Douglas community area and partly in the Near South Side.