Michaelis–Menten kinetics
In biochemistry, Michaelis–Menten kinetics, named after Leonor Michaelis and Maud Menten, is the simplest case of enzyme kinetics, applied to enzyme-catalysed reactions of one substrate and one product. It takes the form of a differential equation describing the reaction rate to , the concentration of the substrate A. Its formula is given by the Michaelis–Menten equation:
Curve of the Michaelis–Menten equation labelled in accordance with IUBMB recommendations
Semi-logarithmic plot of Michaelis–Menten data
The reaction changes from approximately first-order in substrate concentration at low concentrations to approximately zeroth order at high concentrations.
Leonor Michaelis was a German biochemist, physical chemist, and physician, known for his work with Maud Menten on enzyme kinetics in 1913, as well as for work on enzyme inhibition, pH and quinones.
Leonor Michaelis