Michel de l'Hôpital was a French lawyer, diplomat and chancellor during the latter Italian Wars and the early French Wars of Religion. The son of a doctor in the service of Constable Bourbon he spent his early life exiled from France at Bourbon's and then the emperors court. When his father entered the service of the House of Lorraine, he entered the patronage network of Charles, Cardinal of Lorraine. Through his marriage to Marie Morin, he acquired a seat in the Paris Parlement. In this capacity he drew up the charges for the king, concerning the defenders of Boulogne who surrendered the city in 1544, before taking a role as a diplomat to the Council of Trent in 1547. The following year he assisted Anne d'Este in the details of her inheritance to ensure she could marry Francis, Duke of Guise.

Francis II was King of France from 1559 to 1560. He was also King of Scotland as the husband of Mary, Queen of Scots, from 1558 until his death in 1560.