Michelle de Saubonne, Madame de Soubise (1485–1549) was a French courtier who served as lady-in-waiting to Anne of Brittany, as the Governess of the Children of France beginning in 1499, and as the governess for the children of Ercole II d'Este, Duke of Ferrara. She and Anne became best friends and, as she was dying, she asked Michelle de Saubon to be a mother and guardian for her daughter Renée, Duchess of Ferrara, from 1528 to 1536. Like her mother, Renée had a close relationship with Michelle, both of whom had become Protestants. Renée's husband, Ercole II, was a Catholic and he resented having many French Protestants, also known as Huguenots in his court and diverting his wife's attention away from Catholicism.

The Governess of the Children of France was an office at the royal French court during pre-Revolutionary France and the Bourbon Restoration. As the head of the royal nursery, she was charged with the education of the children and grandchildren of the monarch. The holder of the office was taken from the highest-ranking nobility of France and was passed between female family members for much of its history by right of succession (survivance). The governess was supported by various deputies or under-governesses and oversaw a household consisting of dozens of servants and caregivers.