Michigan wine refers to any wine that is made in the state of Michigan in the United States. As of 2020, there were 3,375 acres (1,366 ha) under wine-grape cultivation and over 200 commercial wineries in Michigan, producing 3 million US gallons (11,000,000 L) of wine. According to another count there were 112 operating wineries in Michigan in 2007.

The Old Mission Peninsula AVA is an American Viticultural Area located in Grand Traverse County, Michigan known for well-regarded Michigan wine. The Old Mission Peninsula extends northward from Traverse City into the Grand Traverse Bay of Lake Michigan, ending at Old Mission Point. The peninsula is 19 miles (31 km) long by 3 miles (5 km) wide at its widest point. The climate on the peninsula is moderated by the surrounding waters, helping to prevent frost during the growing season. Grape varietals suitable to cool climates, such as Riesling, Chardonnay, Gewürztraminer, Pinot gris, Pinot noir, Cabernet Franc, and Merlot do best in the Old Mission Peninsula AVA.