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Microtome
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A microtome is a cutting tool used to produce extremely thin slices of material known as sections, with the process being termed microsectioning. Important in science, microtomes are used in microscopy for the preparation of samples for observation under transmitted light or electron radiation.
A diagram of a microtome drawn by Cummings in 1770
Microtome (C. Reichert, Vienna, 1905–1915)
Microtome (C. Reichert, Vienna, 1905–1915)
A sled microtome
A sled microtome
A rotary microtome of older construction
A rotary microtome of older construction
Wilhelm His Sr.
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Wilhelm His Sr. was a Swiss anatomist and professor who invented the microtome. By treating animal tissue with acids and salts to harden it and then slicing it very thinly with the microtome, scientists were able to further study the organization and function of tissues and cells under a microscope.
c. 1900
His's drawing comparing a chick embryo to a slit rubber tube, 1874. He argued that the shapes of structures are dictated mechanically when one part gr
His's drawing comparing a chick embryo to a slit rubber tube, 1874. He argued that the shapes of structures are dictated mechanically when one part grows more than another, in opposition to Haeckel.