Middleborough is a town in Plymouth County, Massachusetts, United States. The population was 24,245 at the 2020 census. The census-designated place of Middleborough Center corresponds to the main village and commercial center of the town. It is the second largest municipality by land area in Massachusetts and nineteenth largest in New England. Middleborough proclaims itself to be the "Cranberry Capital of the World". Cranberry production remains a significant part of the local economy. In 2015, approximately 1,400 acres of the town were used to grow the crop, accounting for 3% of all land used to harvest cranberry bogs in the United States.

Plymouth County is a county in the U.S. state of Massachusetts, south of Boston. As of the 2020 census, the population was 530,819. Its county seats are Plymouth and Brockton. In 1685, the county was created by the Plymouth General Court, the legislature of Plymouth Colony, predating its annexation by the Massachusetts Bay Colony.