Mihaloğlu Ali Bey or Gazi Alauddin Mihaloğlu Ali Bey, (1425–1507) was an Ottoman military commander in 15th century and the first sanjakbey of the Sanjak of Smederevo. He was one of the descendants of Köse Mihal, a Byzantine governor of Chirmenkia and battle companion of Osman Gazi.

The Sanjak of Smederevo, also known in historiography as the Pashalik of Belgrade, was an Ottoman administrative unit (sanjak), that existed between the 15th and the outset of the 19th centuries. It was located in the territory of present-day Central Serbia.