Mike Tyson Mysteries is an American adult animated television series, and is the first collaboration between Warner Bros. Animation and Williams Street. It premiered on October 27, 2014 on Adult Swim. The series features Mike Tyson solving mysteries, in the style of I Am the Greatest: The Adventures of Muhammad Ali, Scooby-Doo, Jonny Quest, and Mister T. On December 10, 2014, Adult Swim renewed the series for a second season, which premiered on November 1, 2015. A third season premiered on May 14, 2017, and the fourth and final season premiered on June 30, 2019.

Williams Street Productions, LLC, d/b/a Williams Street and formerly known as Ghost Planet Industries, is an American animation and live action television production studio owned by the Warner Bros. Television Studios division of Warner Bros., a unit of Warner Bros. Discovery. The studio is the in-house production arm of Adult Swim. Mike Lazzo and Keith Crofford oversaw operations for the building for most of its existence.