Milan is the second largest city after Humboldt in Gibson County, Tennessee and the largest entirely within the county. It is home to the Milan Army Ammunition Plant, the West Tennessee Agricultural Museum and several historical sites listed on the National Register of Historic Places (NRHP). The city was the first in Tennessee to begin no-till farming and to fluoridate its drinking water. The Milan Endowment for Growth in Academics (MEGA) was the first private community financial endowment for public schools in Tennessee.

Gibson County is a county located in the U.S. state of Tennessee. As of the 2020 census, the population was 50,429. Its county seat is Trenton. The county was formed in 1823 and named for John H. Gibson, a soldier of the Natchez Expedition and the Creek War.