The military career of Muhammad, the Islamic prophet, encompasses several expeditions and battles throughout the Hejaz region in the western Arabian Peninsula which took place in the final ten years of his life, from 622 to 632. His primary campaign was against his own tribe in Mecca, the Quraysh. Muhammad proclaimed prophethood around 610 and later migrated to Medina after being persecuted by the Quraysh in 622. After several battles against the Quraysh, Muhammad conquered Mecca in 629, ending his campaign against the tribe.

The conquest of Mecca was a military campaign undertaken by Muhammad and his companions during the Muslim–Quraysh War. They led the early Muslims in an advance on the Quraysh-controlled city of Mecca in December 629 or January 630. The fall of the city to Muhammad formally marked the end of the conflict between his followers and the Quraysh tribal confederation.