Milorganite is a brand of biosolids fertilizer produced by treating sewage sludge by the Milwaukee Metropolitan Sewerage District. The term is a portmanteau of the term Milwaukee Organic Nitrogen. The sewer system of the District collects municipal wastewater from the Milwaukee metropolitan area. After settling, wastewater is treated with microbes to break down organic matter at the Jones Island Water Reclamation Facility in Milwaukee, Wisconsin. The byproduct sewage sludge is produced. This is heat-dried with hot air in the range of 900–1,200 °F (482–649 °C), which heats the sewage sludge to at least 176 °F (80 °C) to kill pathogens. The material is then pelletized and marketed throughout the United States under the name Milorganite. The result is recycling of the nitrogen and phosphorus from the waste-stream as fertilizer. The treated wastewater is discharged to Lake Michigan.

Biosolids are solid organic matter recovered from a sewage treatment process and used as fertilizer. In the past, it was common for farmers to use animal manure to improve their soil fertility. In the 1920s, the farming community began also to use sewage sludge from local wastewater treatment plants. Scientific research over many years has confirmed that these biosolids contain similar nutrients to those in animal manures. Biosolids that are used as fertilizer in farming are usually treated to help to prevent disease-causing pathogens from spreading to the public. Some sewage sludge can not qualify as biosolids due to persistent, bioaccumulative and toxic chemicals, radionuclides, and heavy metals at levels sufficient to contaminate soil and water when applied to land.