The Minister of Foreign Affairs is the head of the Ministry of Foreign Affairs in Italy. The office was one of the positions which Italy inherited from the Kingdom of Sardinia where it was the most ancient ministry of the government: this origin gives to the office a ceremonial primacy in the Italian cabinet.

Antonio Tajani is an Italian politician, journalist and former Italian Air Force officer, who has served as Deputy Prime Minister of Italy and Minister of Foreign Affairs since 22 October 2022. He served as President of the European Parliament from 2017 to 2019, as European Commissioner from 2008 to 2014, and also as a member of the European Parliament from 1994 to 2008 and again from 2014 to 2022 until he was elected to Italy's Chamber of Deputies.