The Minister of Health in Italy is one of the positions in the Italian government. The ministry was officially established in 1958, with Vincenzo Monaldi, of the Christian Democracy, serving as the first minister. From 1946 to 1958, the position was held by a High Commissioners for Hygiene and Public Health, who was not a minister but a special commissioner. Nicola Perrotti, of the Italian Socialist Party, served as the first high commissioner.

The Council of Ministers is the principal executive organ of the Government of Italy. It comprises the President of the Council, all the ministers, and the Undersecretary to the Prime Minister. Deputy ministers and junior ministers are part of the government, but are not members of the Council of Ministers.