The Minister of State Security was a Minister of the South African government, who oversaw South Africa's civilian intelligence agencies and national security matters. In 2021 the ministry was abolished and the function of the minister was taken over by the Presidency.

Siyabonga Cyprian Cwele is a South African politician who served in the cabinet of South Africa from September 2008 to May 2019, most recently as the Minister of Home Affairs between 2018 and 2019. He was appointed as the South African Ambassador to China in December 2020. He is a member of the African National Congress (ANC) and represented the party in Parliament from 1994 to 2019.