The Ministry of Defense of Argentina is a ministry of the national executive power that oversees and advises on matters of national defense, including overseeing the Argentine Armed Forces.

The Ministries of the Argentine Republic, which form the cabinet, currently consist of nine ministries under a ministerial chief of staff. The ministers are appointed by and serve at the pleasure of the president. The current organization derives from the constitutional revision of 1994, and is governed by "The Law on Ministries".